Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 5/20 | 0.41 |
| ▸ | CTSG | P08311 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572258 | 0.85 | ALOX5 (0.51) | CYP3A4MAPTTP53ALOX15MEN1 | |
| SCHEMBL9397894 | 0.85 | ALOX5 (0.51) | CYP3A4MAPTTP53ALOX15MEN1 | |
| SCHEMBL2907263 | 0.84 | ALOX5 (0.49) | CYP3A4MAPTTP53ALOX15MEN1 | |
| SCHEMBL9572268 | 0.75 | PDK2 (0.43) | CYP3A4MAPTTP53ALOX15MEN1 | |
| SCHEMBL30289963 | 0.74 | MEN1 (0.54) | CYP3A4MAPTTP53ALOX15MEN1 | |
| SCHEMBL649568 | 0.74 | MEN1 (0.54) | CYP3A4MAPTTP53ALOX15MEN1 | |
| SCHEMBL9572279 | 0.72 | ESR1 (0.55) | CYP3A4MAPTTP53ALOX15MEN1 | |
| SCHEMBL9572301 | 0.72 | PDK2 (0.45) | CYP3A4MAPTTP53ALOX15MEN1 | |
| SCHEMBL5487840 | 0.70 | ESR1 (0.56) | CYP3A4MAPTTP53ALOX15MEN1 | |
| SCHEMBL21084774 | 0.70 | LIPG (0.50) | ALOX5PTPN1NR1H2NR1H3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322528-A | Reducing agent precursors | TEXACO INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0564233-A1 | Composition of matter for high temperature phenolphthalein-, phenolphthalide-, fluorene-, xanthane-, and anthrone-S-triazines that are soluble in diesel fuel | TEXACO DEVELOPMENT CORPORATION (US) | 1993-10-06 | — | — | EP | disclosed |