Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.36 |
| ▸ | GGH | Q92820 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716214 | 1.00 | GPR139 (0.53) | GPR139KMT2AALDH1A1MAPTMME | |
| SCHEMBL8725848 | 0.87 | GPR139 (0.56) | GPR139KMT2AALDH1A1MAPTMME | |
| SCHEMBL8723479 | 0.81 | GPR139 (0.52) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL6381157 | 0.79 | GPR139 (0.58) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8123492 | 0.78 | KMT2A (0.54) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8127118 | 0.77 | GPR139 (0.57) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8596105 | 0.77 | GPR139 (0.56) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL15962938 | 0.76 | GPR139 (0.59) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL17369074 | 0.74 | GPR139 (0.60) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8595095 | 0.74 | GPR139 (0.55) | GPR139KMT2AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022494-A1 | RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-13 | — | — | WO | disclosed |