Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939956 | 0.89 | RELA (0.44) | HSD17B10LMNACYP2A6MAOBMAOA | |
| SCHEMBL8695868 | 0.89 | PPARG (0.47) | CYP1A2PPARG | |
| SCHEMBL9653611 | 0.89 | TSHR (0.42) | HSD17B10MAOBNFE2L2CYP1A2MEN1 | |
| SCHEMBL3759283 | 0.72 | HSD17B10 (0.46) | HSD17B10LMNACYP2A6MAOBMAOA | |
| SCHEMBL194685 | 0.72 | LMNA (0.42) | HSD17B10LMNACYP2A6MAOBMAOA | |
| SCHEMBL96633 | 0.72 | HSD17B10 (0.46) | HSD17B10LMNACYP2A6MAOBMAOA | |
| SCHEMBL535420 | 0.72 | LMNA (0.42) | HSD17B10LMNACYP2A6MAOBMAOA | |
| SCHEMBL7923050 | 0.69 | HSD17B10 (0.34) | HSD17B10MAOBAHRPIM1PIM2 | |
| SCHEMBL536918 | 0.69 | TSHR (0.43) | LMNACYP2A6MAOBMAOANFE2L2 | |
| SCHEMBL9065756 | 0.68 | LMNA (0.38) | HSD17B10LMNACYP2A6MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178079-A1 | GUANIDINE COMPOUNDS AS ANESTHETICS AND FOR TREATMENT OF NERVOUS SYSTEM DISORDERS | TAKTIX CORPORATION | 2011-07-21 | — | — | US | disclosed |
| US-20110166181-A1 | GUANIDINE COMPOUNDS AS ANESTHETICS AND FOR TREATMENT OF NERVOUS SYSTEM DISORDERS | TAKTIX CORPORATION | 2011-07-07 | — | — | US | disclosed |
| US-7868028-B2 | Guanidine compounds as anesthetics and for treatment of nervous system disorders | Drasner, Fred (US) | 2011-01-11 | — | — | US | disclosed |
| US-20050228022-A1 | blocking voltage-sensitive sodium channels of neurons in a mammal comprising administering 1-benzyl-2-imino-3-(2-hydroxy-3-phenoxypropyl)benzimidazole; analgesics; neuroprotectants; anticonvulsants | TAKTIX CORPORATION (US) | 2005-10-13 | — | — | US | disclosed |
| US-4501746-A | HERBICIDES; PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166181-A1 | GUANIDINE COMPOUNDS AS ANESTHETICS AND FOR TREATMENT OF NERVOUS SYSTEM DISORDERS | CACNA1E, GRIA4, GRIA3 | HSD17B10 2978/4885LMNA 1775/4885CYP2A6 3097/4885 |
| US-20050228022-A1 | blocking voltage-sensitive sodium channels of neurons in a mammal comprising administering 1-benzyl-2-imino-3-(2-hydroxy-3-phenoxypropyl)benzimidazole; analgesics; neuroprotectants; anticonvulsants | CACNA1E, CACNA1B, SCN1A | HSD17B10 3459/4885LMNA 610/4885CYP2A6 3104/4885 |
| US-20110178079-A1 | GUANIDINE COMPOUNDS AS ANESTHETICS AND FOR TREATMENT OF NERVOUS SYSTEM DISORDERS | CACNA1E, GRIA4, GRIA3 | HSD17B10 2895/4885LMNA 1893/4885CYP2A6 3044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.