SCHEMBL9399427

SCHEMBL9399427

CCCCCc1ccc(-c2ncc(C(C)C3CCC(CCCCC)CC3)cn2)cc1C#N

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 6/20 0.38
CYP2D6 P10635 1/20 0.38
XDH P47989 8/20 0.35
IKBKE Q14164 1/20 0.33
TBK1 Q9UHD2 1/20 0.33
GAA P10253 2/20 0.31
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP2C9 P11712 1/20 0.30
LNPEP Q9UIQ6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9398796 0.86 LNPEP (0.35) GAAMAPTKDM4EMEN1USP2
SCHEMBL9399067 0.86 RAB9A (0.33) GAAMAPTKDM4EMEN1USP2
SCHEMBL9399451 0.86 XDH (0.46) XDHALDH1A1HPGD
SCHEMBL9399404 0.86 S1PR1 (0.38) S1PR1CYP2D6IKBKETBK1CYP2C9
SCHEMBL9398626 0.85 GAA (0.33) GAAMAPTKDM4EMEN1USP2
SCHEMBL9399858 0.85 LNPEP (0.33) GAAMAPTKDM4EMEN1USP2
SCHEMBL9399440 0.85 RARB (0.39) S1PR1CYP2D6XDHIKBKETBK1
SCHEMBL9399128 0.85 XDH (0.37) S1PR1CYP2D6XDHIKBKETBK1
SCHEMBL9399434 0.85 RARB (0.39) S1PR1CYP2D6XDHIKBKETBK1
SCHEMBL9399134 0.85 XDH (0.37) S1PR1CYP2D6XDHIKBKETBK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5338483-A Anisotropic compounds having nematic phase and liquid crystal mixtures MERCK PATENT GMBH (DE) 1994-08-16 US disclosed
US-5310501-A Anisotropic compounds having Nematic phase and liquid crystal mixtures MERCK PATENT GMBH (DE) 1994-05-10 US disclosed
US-5227484-A ANISOTROPIC COMPOUNDS HAVING NEMATIC PHASE AND LIQUID CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 1993-07-13 US disclosed
US-5179101-A Anisotropic compounds having nematic phase and liquid crystal mixtures MERCK PATENT GMBH (DE) 1993-01-12 US disclosed
US-5047170-A Anisotropic compounds having nematic phase and liquid crystal mixtures MERCK PATENT GMBH (DE) 1991-09-10 US disclosed
US-4808333-A Anisotropic compounds having nematic phase and liquid crystal mixtures MERCK PATENT GMBH (DE) 1989-02-28 US disclosed
EP-0084194-B1 LIQUID CRYSTAL MIXTURES MERCK PATENT GmbH (DE) 1986-04-30 EP disclosed
EP-0084194-A1 Liquid crystal mixtures MERCK PATENT GmbH (DE) 1983-07-27 EP disclosed