Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29981949 | 0.83 | TDP1 (0.53) | SSTR4MTNR1ATDP1KDM4EALDH1A1 | |
| SCHEMBL9848642 | 0.83 | ATM (0.52) | ATMSSTR4MTNR1ATDP1L3MBTL1 | |
| SCHEMBL6531713 | 0.83 | TDP1 (0.53) | SSTR4MTNR1ATDP1KDM4EALDH1A1 | |
| SCHEMBL9848710 | 0.81 | ATM (0.48) | ATMSSTR4MTNR1ATDP1L3MBTL1 | |
| SCHEMBL9400071 | 0.77 | CYP2A6 (0.49) | MTNR1AMAPK8MAPK9 | |
| SCHEMBL27647542 | 0.76 | TDP1 (0.51) | ATMSSTR4MTNR1ATDP1L3MBTL1 | |
| SCHEMBL4212832 | 0.76 | GPR84 (0.50) | L3MBTL1KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL2534908 | 0.76 | GPR84 (0.50) | L3MBTL1KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL2540033 | 0.76 | GPR84 (0.50) | L3MBTL1KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL7037475 | 0.76 | CYP1A2 (0.50) | SSTR4MTNR1ATDP1ALDH1A1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5331006-A | Cholecystokinin, antisecretory agents | WARNER-LAMBERT COMPANY (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |