Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824528 | 0.88 | TDP1 (0.56) | ATMTDP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL9848642 | 0.82 | ATM (0.52) | ATMTDP1KDM4EALDH1A1SSTR4 | |
| SCHEMBL9399530 | 0.81 | ATM (0.49) | ATMTDP1KDM4EALDH1A1SSTR4 | |
| SCHEMBL17101270 | 0.81 | LMNA (0.46) | KDM4EALDH1A1SSTR4MEN1KMT2A | |
| SCHEMBL29914128 | 0.79 | TDP1 (0.56) | ATMTDP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL20520342 | 0.79 | TDP1 (0.56) | ATMTDP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7355372 | 0.77 | CTSS (0.50) | ATMTDP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7287681 | 0.77 | TDP1 (0.54) | ATMTDP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL9691089 | 0.77 | MMP8 (0.56) | ALDH1A1MMP8CYP1A2 | |
| SCHEMBL7317433 | 0.76 | TDP1 (0.61) | TDP1KDM4EALDH1A1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4857650-A | Novel renin inhibitory amino acid derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |