Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399561 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTHPGDSSTR4 | |
| SCHEMBL14290306 | 0.80 | KDM4E (0.44) | ALDH1A1KDM4EMAPTHPGDSSTR4 | |
| SCHEMBL9400035 | 0.73 | CCKBR (0.43) | — | |
| SCHEMBL9400040 | 0.73 | CCKBR (0.43) | — | |
| SCHEMBL25791284 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTHPGDSSTR4 | |
| SCHEMBL15491630 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTHPGDSSTR4 | |
| SCHEMBL24090169 | 0.70 | KDM4E (0.49) | ALDH1A1KDM4EMAPTHPGDRAB9A | |
| SCHEMBL12480176 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTHPGDRAB9A | |
| SCHEMBL1632109 | 0.69 | SLC6A2 (0.52) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8745476 | 0.69 | SLC6A2 (0.52) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5331006-A | Cholecystokinin, antisecretory agents | WARNER-LAMBERT COMPANY (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |