SCHEMBL93998

SCHEMBL93998

Cc1c(N)ccc(C(=O)O)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.50
KMT2A Q03164 4/20 0.50
TDP1 Q9NUW8 4/20 0.50
MEN1 O00255 3/20 0.50
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
GABRA4 P48169 1/20 0.48
GABRE P78334 1/20 0.48
GABRA6 Q16445 1/20 0.48
GABRG1 Q8N1C3 1/20 0.48
GABRG3 Q99928 1/20 0.48
GABRQ Q9UN88 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30340194 1.00 KDM4E (0.50) KDM4EKMT2ATDP1MEN1GABRP
SCHEMBL31389208 0.85 CYP1A2 (0.58) KDM4EKMT2ATDP1MEN1GABRP
SCHEMBL128319 0.85 CYP1A2 (0.58) KDM4EKMT2ATDP1MEN1GABRP
SCHEMBL555823 0.84 KDM4E (0.48) KDM4EKMT2ATDP1MEN1GABRP
SCHEMBL2926609 0.84 KDM4E (0.48) KDM4EKMT2ATDP1MEN1GABRP
SCHEMBL6232283 0.84 CYP3A4 (0.40) KDM4EKMT2ATDP1MEN1GABRP
SCHEMBL11129813 0.83 CYP3A4 (0.51) KDM4EKMT2ARXFP1POLBHSD17B10
Ammonia Solution, Strong SCHEMBL29137499 0.83 CYP1A2 (0.55) KDM4EKMT2ATDP1MEN1GABRP
SCHEMBL3540331 0.83 MMP2 (0.53) KDM4EKMT2ATDP1MEN1GABRP
SCHEMBL547206 0.83 GRM1 (0.56) KDM4EKMT2ATDP1MEN1GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1018 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114432160-B Dental composite material, multilayer dental composite material, and preparation methods and applications thereof 香港城市大学深圳研究院 2024-04-02 CN claimed
EP-3188708-B1 MINERAL SUNSCREEN COMPOSITIONS EDGEWELL PERSONAL CARE BRANDS LLC (US) 2023-05-03 EP claimed
CN-110917071-B Core-shell structure flexible bead, preparation method thereof and personal care product comprising core-shell structure flexible bead 万华化学集团股份有限公司 2022-11-08 CN claimed
CN-114432160-A Dental composite material, multilayer dental composite material, and preparation method and application thereof 香港城市大学深圳研究院 2022-05-06 CN claimed
CN-111556742-A UV-blocking cosmetic composition comprising positively charged oil 株式会社爱茉莉太平洋 2020-08-18 CN claimed
CN-111358711-A Photosensitive material/calcium alginate core-shell nanocapsule dispersion and preparation method thereof 万华化学集团股份有限公司 2020-07-03 CN claimed
CN-110917071-A Core-shell structure flexible bead, preparation method thereof and personal care product comprising core-shell structure flexible bead 上海万华科聚化工科技发展有限公司 2020-03-27 CN claimed
EP-3148507-B1 COSMETIC COMPOSITIONS WITH ENHANCED COLOR RETENTION FOR IMPROVED SKIN APPEARANCE EDGEWELL PERSONAL CARE BRANDS LLC (US) 2019-07-10 EP claimed
CN-109316390-A One kind brightening sun-proof antiallergy nursing frost 蔡银中 2019-02-12 CN claimed
EP-2999521-B1 SYNERGISTIC PHOTOPROTECTIVE COMPOSITIONS EDGEWELL PERSONAL CARE BRANDS LLC (US) 2019-01-09 EP claimed
US-6468509-B2 Sunscreen composition containing sol-gel microcapsules SOL-GEL TECHNOLOGIES LTD. (IL) 2002-10-22 US claimed
US-20020110534-A1 Composition for the treatment of human hair GOLDWELL GMBH (DE) 2002-08-15 US claimed
US-20020035087-A1 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light BARCLAY BARRY J (CA) 2002-03-21 US claimed
WO-2002003942-A2 B COMPLEX VITAMIN COMPOSITIONS THAT PROTECT AGAINST CELLULAR DAMAGE CAUSED BY ULTRAVIOLET LIGHT PLANET BIOTECH INC. (CA) 2002-01-17 WO claimed
EP-0891767-B1 Glossy composition containing aromatic oils thickened with an alkylether of a polysaccharide OREAL (FR) 2001-07-18 EP claimed
WO-2001003663-A1 SUNSCREEN FORMULATIONS H A MILTON HOLDINGS PTY LTD (AU) 2001-01-18 WO claimed
EP-0614354-A1 USE OF SALICYLIC ACID FOR REGULATING SKIN WRINKLES AND/OR SKIN ATROPHY RICHARDSON-VICKS, INC. (US) 1994-09-14 EP claimed
CN-1091317-A Improve the part input of medicine PROCTER & GAMBLE (US) 1994-08-31 CN claimed
CN-1073947-A Novel sunscreen metal complexes RICHARDSON VICKS INC (US) 1993-07-07 CN claimed
WO-1993010756-A1 USE OF SALICYLIC ACID FOR REGULATING SKIN WRINKLES AND/OR SKIN ATROPHY RICHARDSON-VICKS, INC. (US) 1993-06-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020110534-A1 Composition for the treatment of human hair MICA, HLA-B, HLA-C KDM4E 3962/4885KMT2A 2972/4885TDP1 2594/4885
US-20020035087-A1 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light MAOB, S100A9, CCNB3 KDM4E 2040/4885KMT2A 3127/4885TDP1 591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.