Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27932861 | 0.98 | KMT2A (0.48) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL2921220 | 0.86 | GABRP (0.50) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL31494238 | 0.86 | GABRP (0.50) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL30340194 | 0.84 | KDM4E (0.50) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL93998 | 0.84 | KDM4E (0.50) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL2926609 | 0.83 | KDM4E (0.48) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL30374425 | 0.83 | KDM4E (0.48) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL10661542 | 0.83 | PARP1 (0.41) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL1457096 | 0.83 | KDM4E (0.48) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL2880282 | 0.81 | CASP7 (0.53) | KDM4EKMT2ATDP1MEN1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818169-B1 | METHOD FOR DETECTING SYNOVIAL JOINT INFECTIONS | QUALIZYME DIAGNOSTICS GMBH & CO KG (AT) | 2022-06-15 | — | — | EP | claimed |
| EP-3818169-A1 | METHOD FOR DETECTING SYNOVIAL JOINT INFECTIONS | Qualizyme Diagnostics GmbH & Co KG (AT) | 2021-05-12 | — | — | EP | claimed |
| WO-2020008039-A1 | METHOD FOR DETECTING SYNOVIAL JOINT INFECTIONS | QUALIZYME DIAGNOSTICS GMBH & CO KG (AT) | 2020-01-09 | — | — | WO | claimed |
| US-6805718-B2 | USING AROMATIC AMINE, NAPHTHOL OR AMINONAPHTHALENE AND ENZYME | NOVOZYMES A/S (DK) | 2004-10-19 | — | — | US | claimed |
| US-6296672-B1 | PEROXIDASE, OXIDOREDUCTASE, LACCASE | NOVOZYMES A/S PATENTS (DK) | 2001-10-02 | — | — | US | claimed |
| US-20260125348-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4710922-A2 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | Oregon State University (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4003337-B1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | UNIV OREGON STATE (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12473262-B2 | Aryl hydrocarbon receptor activators | OREGON STATE UNIVERSITY (US) | 2025-11-18 | — | — | US | disclosed |
| US-20250339445-A1 | Modulators of Orphan Nuclear Receptors for Treating Pancreatitis, Glioblastoma, Sarcopenia and Stroke | UNIV EMORY (US) | 2025-11-06 | — | — | US | disclosed |
| EP-3787631-B1 | MODULATORS OF ORPHAN NUCLEAR RECEPTORS FOR NASH AND OTHER METABOLIC DISORDERS | UNIV EMORY (US) | 2025-09-10 | — | — | EP | disclosed |
| US-12318393-B2 | Modulators of orphan nuclear receptors for NASH and other metabolic disorders | EMORY UNIVERSITY | 2025-06-03 | — | — | US | disclosed |
| EP-0664792-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5559127-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0703819-A1 | METHOD OF MAKING COMPOSITE GAS SEPARATION MEMBRANES | UOP (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0672031-A1 | CATECHOL DIETHERS AS SELECTIVE PDE IV? INHIBITORS | PFIZER INC. (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0664792-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994029002-A1 | COMPOSITE GAS SEPARATION MEMBRANES AND MAKING THEREOF | UOP (US) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994012461-A1 | CATECHOL DIETHERS AS SELECTIVE PDEIV INHIBITORS | PFIZER INC. (US) | 1994-06-09 | — | — | WO | disclosed |
| WO-1994008962-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12318393-B2 | Modulators of orphan nuclear receptors for NASH and other metabolic disorders | RORA, RORB, RORC | KDM4E 3555/4885KMT2A 1778/4885TDP1 4386/4885 |
| US-20250339445-A1 | Modulators of Orphan Nuclear Receptors for Treating Pancreatitis, Glioblastoma, Sarcopenia and Stroke | RXRA, RXRG, RXRB | KDM4E 4329/4885KMT2A 3736/4885TDP1 3094/4885 |
| US-20260125348-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | AHR, ARNT, NR1H2 | KDM4E 2619/4885KMT2A 2141/4885TDP1 4328/4885 |
| US-12473262-B2 | Aryl hydrocarbon receptor activators | AHR, ARNT, NR0B1 | KDM4E 2779/4885KMT2A 1892/4885TDP1 2387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.