SCHEMBL547206

SCHEMBL547206

Cc1c(N)ccc(C(=O)O)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 1/20 0.56
MMP2 P08253 1/20 0.53
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 4/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
SELL P14151 1/20 0.48
SELP P16109 1/20 0.48
TDP1 Q9NUW8 4/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
GABRA2 P47869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL481149 0.83 MAPT (0.45) GRM1MMP2KDM4EALDH1A1HPGD
SCHEMBL3540331 0.83 MMP2 (0.53) GRM1MMP2KDM4EALDH1A1HPGD
SCHEMBL93998 0.83 KDM4E (0.50) GRM1MMP2KDM4EALDH1A1HPGD
SCHEMBL30340194 0.83 KDM4E (0.50) GRM1MMP2KDM4EALDH1A1HPGD
SCHEMBL2926609 0.81 KDM4E (0.48) GRM1MMP2KDM4EALDH1A1TDP1
SCHEMBL1981082 0.80 MMP2 (0.65) GRM1MMP2KDM4EALDH1A1HPGD
SCHEMBL27796104 0.79 ALDH1A1 (0.52) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL565454 0.78 SELL (0.64) GRM1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL30149140 0.78 ALDH1A1 (0.57) GRM1MMP2KDM4EALDH1A1HPGD
SCHEMBL30463104 0.78 SELL (0.64) GRM1KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2508611-B1 Process for production of triprenyl phenol compounds TMS CO LTD (JP) 2019-05-08 EP claimed
WO-2003016615-A1 SINGLE BATH PROCESS FOR BLEACHING AND DYEING TEXTILES NOVOZYMES NORTH AMERICA, INC. (US) 2003-02-27 WO claimed
US-4036951-A SUNSCREEN AGENTS SYNERGISTICS, INC. (US) 1977-07-19 US claimed
EP-2956437-B1 ALBICIDIN DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS UNIV BERLIN TECH (DE) 2023-05-10 EP disclosed
US-10308595-B2 Albicidin derivatives, their use and synthesis Technische Universität Berlin (DE) 2019-06-04 US disclosed
EP-2508611-B1 Process for production of triprenyl phenol compounds TMS CO LTD (JP) 2019-05-08 EP disclosed
EP-2708223-B1 DYEING AGENT AND USE FOR SAME AMANO ENZYME INC (JP) 2017-02-01 EP disclosed
US-9447028-B2 Therapeutic aryl-amido-aryl compounds and their use KING'S COLLEGE LONDON (GB) 2016-09-20 US disclosed
US-20160039747-A1 Therapeutic Aryl-Amido-Aryl Compounds and Their Use KING'S COLLEGE LONDON (GB) 2016-02-11 US disclosed
US-20150376120-A1 ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS Technische Universität Berlin (DE) 2015-12-31 US disclosed
US-20150376120-A1 ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS Technische Universität Berlin (DE) 2015-12-31 US disclosed
WO-2002009769-A2 THERAPEUTIC AZO-COMPOUNDS FOR DRUG DELIVERY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2002-02-07 WO disclosed
WO-2001098518-A2 BIOTRANSFORMATION OF BIOLOGICALLY ACTIVE COMPOUNDS MADE OF VARIOUS CLASSES OF CHEMICAL SUBSTANCES BY MEANS OF LACCASE AND MANGANESE PEROXIDASE ENZYMES GANOMYCIN GMBH (DE) 2001-12-27 WO disclosed
US-20010037532-A1 Enzymatic method for textile dyeing NOVOZYMES A/S (DK) 2001-11-08 US disclosed
WO-2001044563-A1 ENZYMATIC METHOD FOR TEXTILE DYEING NOVOZYMES NORTH AMERICA, INC. (US) 2001-06-21 WO disclosed
US-6036729-A DYEING, SOAKING MATERIAL WITH NAPHTHOLS, HYDROGEN PEROXIDE AND ENZYMES OF PEROXIDASE OR OXIDASE NOVO NORDISK A/S (DK) 2000-03-14 US disclosed
US-5972042-A DYEING SYSTEM WHICH COMPRISES ONE OR MORE MONO-, DI- OR POLYCYCLIC AROMATIC OR HETEROAROMATIC COMPOUNDS, AND HYDROGEN PEROXIDE SOURCE AND ENZYME EXHIBITING PEROXIDASE ACTIVITY OR ENZYME EXHIBITING OXIDASE ACTIVITY NOVO NORDISK A/S (DE) 1999-10-26 US disclosed
US-5925148-A TREATING IN AQUEOUS DYE LIQUOR WITH SYSTEM COMPRISING SUBSTITUTED AROMATIC COMPOUND, HYDROGEN PEROXIDE SOURCE AND PEROXIDASE ENZYME AND/OR OXIDASE ENZYME NOVO NORDISK A/S (DK) 1999-07-20 US disclosed
EP-0870082-A1 ENZYMATIC METHOD FOR DYEING NOVO NORDISK BIOCHEM NORTH AMERICA (US) 1998-10-14 EP disclosed
WO-1997023684-A1 ENZYMATIC METHOD FOR DYEING NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) 1997-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308595-B2 Albicidin derivatives, their use and synthesis MB, ALB, BCAT2 GRM1 2232/4885MMP2 1420/4885KDM4E 4141/4885
US-20150376120-A1 ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS MB, ALB, BCAT2 GRM1 2232/4885MMP2 1420/4885KDM4E 4141/4885
US-20160039747-A1 Therapeutic Aryl-Amido-Aryl Compounds and Their Use RARA, RARB, RARG GRM1 333/4885MMP2 3429/4885KDM4E 2548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.