SCHEMBL93999

SCHEMBL93999

Nc1cc(Cl)c(O)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 1.00
CYP3A4 P08684 8/20 0.58
HSD17B10 Q99714 7/20 0.58
TSHR P16473 7/20 0.58
ALDH1A1 P00352 4/20 0.58
RECQL P46063 4/20 0.58
TTR P02766 3/20 0.58
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
ALOX15 P16050 4/20 0.50
ALOX12 P18054 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HIF1A Q16665 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
CYP2C9 P11712 1/20 0.50
HPGD P15428 5/20 0.46
MAPK1 P28482 3/20 0.46
TP53 P04637 1/20 0.45
CASP1 P29466 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9453347 0.97 THRB (0.94) THRBCYP3A4HSD17B10TSHRALDH1A1
Hydrochloric Acid SCHEMBL10336483 0.97 THRB (0.94) THRBCYP3A4HSD17B10TSHRALDH1A1
Hydrochloric Acid SCHEMBL7755405 0.97 THRB (0.94) THRBCYP3A4HSD17B10TSHRALDH1A1
SCHEMBL5271617 0.97 THRB (0.94) THRBCYP3A4HSD17B10TSHRALDH1A1
Hydrochloric Acid SCHEMBL10336482 0.92 THRB (0.84) THRBCYP3A4HSD17B10TSHRALDH1A1
SCHEMBL6687463 0.86 THRB (0.75) THRBCYP3A4HSD17B10TSHRALDH1A1
SCHEMBL22134259 0.86 THRB (0.75) THRBCYP3A4HSD17B10TSHRALDH1A1
SCHEMBL6152001 0.83 CA1 (0.83) THRBCYP3A4HSD17B10TSHRALDH1A1
SCHEMBL9933014 0.82 THRB (0.68) THRBCYP3A4HSD17B10TSHRALDH1A1
SCHEMBL655140 0.82 THRB (0.68) THRBCYP3A4HSD17B10TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3058 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010848-A Preparation method and detection method of key intermediate of dihydropyrido [4,3-d ] pyrimidinone analogue 河北安健成益医药科技有限公司 2026-05-12 CN claimed
EP-4691557-A2 METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF Madrigal Pharmaceuticals, Inc. (US) 2026-02-11 EP claimed
US-20250115559-A1 PREPARATION METHOD OF PYRIDAZINONE DERIVATIVE, AND INTERMEDIATE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2025-04-10 US claimed
CN-119569723-A Bactericide for oil field and synthetic method and application thereof 东营施普瑞石油工程技术有限公司 2025-03-07 CN claimed
CN-119504714-A Rasemet-teh preparation method of herba Luo 河北科技大学 2025-02-25 CN claimed
CN-119431159-A Synthesis method of high-purity 2, 6-dichloro-4-aminophenol 内蒙古通瑞达生物科技有限公司 2025-02-14 CN claimed
EP-4140998-B1 SUBSTITUTED PYRIDAZINONE COMPOUND AND USE THEREOF HENAN SELKIN BIOMEDICAL TECH CO LTD (CN) 2025-02-12 EP claimed
CN-119290854-A Colorimetric detection method of carbofuran pesticide 中国科学院大连化学物理研究所 2025-01-10 CN claimed
US-20240423887-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT KAO CORPORATION (JP) 2024-12-26 US claimed
EP-4477649-A1 PREPARATION METHOD OF PYRIDAZINONE DERIVATIVE, AND INTERMEDIATE THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-12-18 EP claimed
EP-0985406-A1 Hair dye composition GOLDWELL GmbH (DE) 2000-03-15 EP claimed
EP-0951900-A2 Hair dyeing compositions containing 2-chloro- and 2,6-dichloro-4-aminophenol & phenylpyrazolones Bristol-Myers Squibb Company (US) 1999-10-27 EP claimed
WO-1998052519-A1 HAIR COLOURING COMPOSITIONS AND THEIR USE THE PROCTER & GAMBLE COMPANY (US) 1998-11-26 WO claimed
CN-1183405-A Dichloro-tetrafluoro-ethoxy aniline and its preparing process INST OF FUXIN FLUOROCHEM GENER (CN) 1998-06-03 CN claimed
US-5223373-A Positive working photosensitive composition and photosensitive electrodeposition composition prepared therefrom INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1993-06-29 US claimed
EP-0347283-B1 PROCESS FOR THE PREPARATION OF 2,6-DICHLORO-4-AMINOPHENOL RHONE-POULENC CHIMIE (FR) 1992-03-04 EP claimed
US-5068436-A Hydrogenation of halonitrobenzenes without dehalogenation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-11-26 US claimed
EP-0211775-B1 PROCESS FOR NITRATING PHENOLIC COMPOUNDS RHONE-POULENC CHIMIE (FR) 1991-02-27 EP claimed
EP-0079540-B1 HAIR DYEING COMPOSITIONS Henkel Kommanditgesellschaft auf Aktien (DE) 1985-03-20 EP claimed
EP-0079540-A2 Hair dyeing compositions Henkel Kommanditgesellschaft auf Aktien (DE) 1983-05-25 EP claimed