SCHEMBL9400

SCHEMBL9400

OCCCN1CCCCC1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 5/20 0.65
CYP1A2 P05177 1/20 0.54
MAPK1 P28482 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.46
POLB P06746 1/20 0.46
TSHR P16473 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 1/20 0.43
MEN1 O00255 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
HTR1A P08908 1/20 0.41
CHRM5 P08912 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10957514 1.00 HRH3 (0.65) HRH3CYP1A2MAPK1SMN1; SMN2ALDH1A1
SCHEMBL5032551 1.00 HRH3 (0.65) HRH3CYP1A2MAPK1SMN1; SMN2ALDH1A1
SCHEMBL1098241 1.00 HRH3 (0.65) HRH3CYP1A2MAPK1SMN1; SMN2ALDH1A1
Hydrochloric Acid SCHEMBL1333521 0.97 HRH3 (0.62) HRH3CYP1A2MAPK1SMN1; SMN2ALDH1A1
SCHEMBL9129 0.97
SCHEMBL11399499 0.95 HRH3 (0.59) HRH3CYP1A2MAPK1SMN1; SMN2ALDH1A1
SCHEMBL3191128 0.95 HRH3 (0.67) HRH3CYP1A2MAPK1SMN1; SMN2ALDH1A1
Hydrochloric Acid SCHEMBL20303711 0.94 HRH3 (0.57) HRH3CYP1A2MAPK1SMN1; SMN2ALDH1A1
Water SCHEMBL30636156 0.94 HRH3 (0.57) HRH3CYP1A2MAPK1SMN1; SMN2ALDH1A1
SCHEMBL4504898 0.92 HRH3 (0.70) HRH3CYP1A2MAPK1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1930 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4667511-A2 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY Tiba Biotech LLC (US) 2025-12-24 EP claimed
US-20240207187-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY TIBA BIOTECH LLC (US) 2024-06-27 US claimed
CN-117915958-A Dendritic structures as non-viral vectors in gene delivery 蒂巴生物技术有限公司 2024-04-19 CN claimed
US-11945788-B2 Process for preparing pitolisant hydrochloride and solid-state forms thereof NURAY CHEMICALS PRIVATE LIMITED (IN) 2024-04-02 US claimed
CN-117794923-A Benzodioxane compound, and preparation method and application thereof 南京红云生物科技有限公司 2024-03-29 CN claimed
EP-3921320-B1 IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST BEIGENE LTD (KY) 2024-03-06 EP claimed
EP-4313170-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY Tiba Biotech LLC (US) 2024-02-07 EP claimed
EP-3461552-B1 CARBON DIOXIDE ABSORBENT AND APPARATUS OF SEPARATING AND RECOVERING CARBON DIOXIDE TOSHIBA KK (JP) 2023-12-13 EP claimed
US-20230219914-A1 PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF Nuray Chemicals Private Limiited (IN) 2023-07-13 US claimed
CN-116284848-A Method for dissolving chitosan/cellulose by using multifunctional acidic ionic liquid 南京工业大学 2023-06-23 CN claimed
WO-1996033980-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1996-10-31 WO claimed
WO-1996015118-A1 ANILINE DERIVATIVES ZENECA LIMITED (GB) 1996-05-23 WO claimed
US-5516915-A Bis-(1H-indol-3-yl)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them GOEDECKE AKTIENGESELLSCHAFT (DE) 1996-05-14 US claimed
US-RE35217-E ALKALINE DEVELOPMENT OF EXPOSED NOVOLAK/O-QUINONEDIAZIDE PHOTORESIST LATENT IMAGE BASF AKTIENGESELLSCHAFT (DE) 1996-04-23 US claimed
EP-0370236-B1 INDOLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS GÖDECKE AKTIENGESELLSCHAFT (DE) 1991-12-27 EP claimed
EP-0362695-B1 PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS GÖDECKE AKTIENGESELLSCHAFT (DE) 1991-04-03 EP claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
US-4912107-A Pyrrolocarbazole derivatives, compositions containing them, and methods for using them GOEDECKE AKTIENGESELLSCHAFT (DE) 1990-03-27 US claimed
US-4483833-A DESULFURIZATION EXXON RESEARCH & ENGINEERING CO. (US) 1984-11-20 US claimed
US-4264599-A HYPOTENSIVE AGENTS, ADRENERGIC BLOCKING AGENTS CIBA-GEIGY CORPORATION (US) 1981-04-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207187-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY TLR3, TLR9, TLR6 HRH3 2092/4885CYP1A2 4879/4885MAPK1 4157/4885
US-11945788-B2 Process for preparing pitolisant hydrochloride and solid-state forms thereof PITHD1, MLN, TPP1 HRH3 1919/4885CYP1A2 322/4885MAPK1 2216/4885
US-20230219914-A1 PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF PITHD1, MLN, TPP1 HRH3 1919/4885CYP1A2 322/4885MAPK1 2216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.