Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788141 | 0.85 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL4098649 | 0.81 | MMP8 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL9204947 | 0.80 | MMP8 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL28653958 | 0.80 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1RECQLMMP8 | |
| SCHEMBL7616395 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1RECQLMMP8PIN1 | |
| SCHEMBL8233844 | 0.79 | MMP8 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL29256551 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1RECQLMMP8PIN1 | |
| SCHEMBL7613025 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1RECQLMMP8PIN1 | |
| SCHEMBL7614875 | 0.76 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1RECQLMMP8PIN1 | |
| SCHEMBL21747501 | 0.75 | NPSR1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371075-A | Pesticides | ROUSSEL-UCLAF (FR) | 1994-12-06 | — | — | US | disclosed |
| US-5157029-A | Insecticides, miticides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-10-20 | — | — | US | disclosed |
| US-5057508-A | Bicyclo(2-2-1)octanes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-10-15 | — | — | US | disclosed |
| US-4965257-A | INSECTICIDES, ACARICIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0216624-A2 | Pesticidal compounds | ROUSSEL-UCLAF (FR) | 1987-04-01 | — | — | EP | disclosed |