Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399938 | 0.92 | MAPT (0.37) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9399421 | 0.86 | ALDH1A1 (0.39) | THRBALDH1A1CYP3A4MAPK1MAPT | |
| SCHEMBL9399916 | 0.79 | ALDH1A1 (0.35) | THRBALDH1A1MAPK1MAPTHPGD | |
| SCHEMBL9400123 | 0.77 | PTGS1 (0.46) | ALDH1A1MAPK1MAPTHPGDL3MBTL1 | |
| SCHEMBL13324353 | 0.71 | THRB (0.53) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL6742403 | 0.70 | THRB (0.64) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL14015781 | 0.69 | THRB (0.57) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL1562777 | 0.69 | THRB (0.66) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL13801183 | 0.69 | THRB (0.57) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL22861304 | 0.69 | THRB (0.57) | THRBALDH1A1TP53CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145970-A | Oil additives | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | claimed |
| US-5321067-A | Oxidation, heat resistance | CIBA-GEIGY CORPORATION (US) | 1994-06-14 | — | — | US | disclosed |
| US-5145970-A | Oil additives | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |