Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | F2R | P25116 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400323 | 0.93 | PTGS1 (0.38) | PTGS2PTGS1LMNARECQLTSHR | |
| SCHEMBL7516734 | 0.87 | PTGS2 (0.46) | PTGS2PTGS1LMNARECQLF2R | |
| SCHEMBL10581738 | 0.85 | LMNA (0.37) | PTGS2PTGS1LMNARECQLTSHR | |
| SCHEMBL10578310 | 0.84 | PTGS2 (0.44) | PTGS2PTGS1LMNARECQLF2R | |
| SCHEMBL7482673 | 0.81 | PTGS2 (0.47) | PTGS2PTGS1LMNARECQLF2R | |
| SCHEMBL1264011 | 0.74 | TSHR (0.64) | PTGS2PTGS1LMNARECQLTSHR | |
| SCHEMBL9400312 | 0.73 | TSHR (0.37) | TSHRKMT2AMEN1ALDH1A1ESR1 | |
| SCHEMBL9400316 | 0.71 | TSHR (0.41) | LMNATSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL1138443 | 0.71 | SRD5A1 (0.34) | THRB | |
| SCHEMBL9440221 | 0.70 | TSHR (0.40) | TSHRKMT2AMEN1ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300647-A | Light stabilizers for polyolefins, other polymers | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
| US-5300647-A | Light stabilizers for polyolefins, other polymers | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |