Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161429 | 0.82 | GAA (0.41) | GAAEPHX2EPHX1BCHEHPGD | |
| SCHEMBL12921994 | 0.80 | TSHR (0.61) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL6300772 | 0.80 | TDP1 (0.35) | TSHRKMT2AGAAMEN1EPHX2 | |
| SCHEMBL10160344 | 0.80 | EPHX1 (0.46) | TSHRGAAEPHX2EPHX1 | |
| SCHEMBL4026717 | 0.80 | TSHR (0.45) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1138567 | 0.78 | KMT2A (0.63) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1948723 | 0.78 | TSHR (0.53) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL19422677 | 0.78 | GAA (0.49) | ALDH1A1GAAEPHX1BCHESGPL1 | |
| SCHEMBL14165270 | 0.78 | TDP1 (0.44) | GAAEPHX2EPHX1BCHESGPL1 | |
| SCHEMBL19422674 | 0.77 | ACHE (0.47) | GAAEPHX2EPHX1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300647-A | Light stabilizers for polyolefins, other polymers | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0309400-B1 | N-acyloxy hindered amine stabilizers | CIBA GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| EP-0309400-A2 | N-acyloxy hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |