Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300796 | 0.90 | DRD2 (0.32) | GAASGPL1MAN2B1KMT2AMEN1 | |
| SCHEMBL524344 | 0.82 | NAAA (0.39) | GAAEPHX2TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL21582136 | 0.82 | NAAA (0.39) | GAAEPHX2TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL3957275 | 0.81 | EPHX2 (0.39) | GAAEPHX1EPHX2TSHRKMT2A | |
| SCHEMBL12227670 | 0.81 | TSHR (0.47) | GAATSHRKMT2AMEN1 | |
| SCHEMBL38998 | 0.80 | KMT2A (0.38) | GAAEPHX2TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL9400326 | 0.80 | TSHR (0.50) | GAASGPL1EPHX1EPHX2BCHE | |
| SCHEMBL39302 | 0.80 | KMT2A (0.38) | GAATSHRKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL12020715 | 0.80 | TSHR (0.35) | GAATSHRKMT2AMEN1 | |
| SCHEMBL39577 | 0.80 | KMT2A (0.35) | GAATSHRKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391949-B1 | — | — | None | — | — | US | disclosed |
| US-6872832-B2 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-03-29 | — | — | US | disclosed |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2003-06-26 | — | — | US | disclosed |
| US-6420562-B2 | OXIDATION, HEAT AND RADIATION RESISTANCE | CIBA SPECIALITY CHEMICALS CORPORATION | 2002-07-16 | — | — | US | disclosed |
| US-6403681-B2 | STABILIZER FOR PLASTICS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-11 | — | — | US | disclosed |
| US-6392041-B1 | OXIDATION, HEAT AND RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-21 | — | — | US | disclosed |
| US-6391949-B2 | FOR AUTOMOBILE FINISHES; HEAT, OXIDATION, RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-21 | — | — | US | disclosed |
| US-20020058735-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2002-05-16 | — | — | US | disclosed |
| US-20010034449-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-25 | — | — | US | disclosed |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-18 | — | — | US | disclosed |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058735-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | OGG1, HAO2, POLH | TDP1 663/4885GAA 1255/4885SGPL1 4265/4885 |
| US-20010034449-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | TDP1 606/4885GAA 1582/4885SGPL1 4303/4885 |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | OGG1, POLH, OGFOD1 | TDP1 688/4885GAA 1590/4885SGPL1 4281/4885 |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | TDP1 606/4885GAA 1582/4885SGPL1 4303/4885 |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | TDP1 606/4885GAA 1582/4885SGPL1 4303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.