Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400451 | 0.83 | LMNA (0.49) | LMNAALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL15919361 | 0.75 | NPC1 (0.58) | LMNAALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL4180920 | 0.74 | LMNA (0.43) | LMNAALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL27728086 | 0.73 | LMNA (0.68) | LMNAALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL25546222 | 0.72 | ALDH1A1 (0.55) | LMNAALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL4188852 | 0.72 | LMNA (0.50) | LMNAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL3778246 | 0.71 | LMNA (0.71) | LMNAALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL4431302 | 0.70 | LMNA (0.52) | LMNAALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL9400319 | 0.70 | HTR2A (0.54) | LMNAALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL27938396 | 0.70 | TDP1 (0.48) | LMNAKDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332759-A | Treating a disorder due to vasodilation of the vascular system | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |