Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 3/20 | 0.38 |
| ▸ | HTR1B | P28222 | 3/20 | 0.38 |
| ▸ | HTR1F | P30939 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400451 | 0.84 | LMNA (0.49) | HTR2AHTR1ALMNAHTR2BADRA2B | |
| SCHEMBL9400311 | 0.78 | CNR1 (0.43) | LMNANPSR1ALDH1A1MAPTKDM4E | |
| Almotriptan SCHEMBL3273179 | 0.70 | HTR1A (1.00) | HTR2AHTR1ALMNAHTR2BADRA2B | |
| Almotriptan SCHEMBL29396422 | 0.70 | HTR1A (1.00) | HTR2AHTR1ALMNAHTR2BADRA2B | |
| SCHEMBL8208643 | 0.70 | HTR1A (0.64) | HTR2AHTR1ALMNAHTR2BADRA2B | |
| Almotriptan SCHEMBL1957 | 0.70 | HTR1A (1.00) | HTR2AHTR1ALMNAHTR2BADRA2B | |
| SCHEMBL9400339 | 0.70 | LMNA (0.46) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1437 | 0.70 | HTR1A (0.98) | HTR2AHTR1ALMNAHTR2BADRA2B | |
| Almotriptan SCHEMBL2166 | 0.70 | HTR1A (0.98) | HTR2AHTR1ALMNAHTR2BADRA2B | |
| Almotriptan SCHEMBL5042399 | 0.69 | HTR1A (0.96) | HTR2AHTR1ALMNAHTR2BADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332759-A | Treating a disorder due to vasodilation of the vascular system | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |