Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691677 | 0.81 | MTNR1A (0.64) | PTPN1 | |
| SCHEMBL6530771 | 0.79 | TDP1 (0.62) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL6890681 | 0.78 | CA12 (0.63) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL14691955 | 0.78 | SMN1; SMN2 (0.44) | KMT2AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL7354821 | 0.78 | CA12 (0.66) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL5452784 | 0.78 | KMT2A (0.63) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL11400884 | 0.77 | ALDH1A1 (0.47) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL13485778 | 0.77 | TDP1 (0.65) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL28372184 | 0.77 | TDP1 (0.65) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL7750217 | 0.77 | ATM (0.58) | KMT2AMEN1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332759-A | Treating a disorder due to vasodilation of the vascular system | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |
| US-3903163-A | N,N-Disubstituted naphthaleneacetamidines | DOW CHEMICAL CO | 1975-09-02 | — | — | US | disclosed |