Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 2/20 | 0.42 |
| ▸ | CD44 | P16070 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indoline SCHEMBL28096138 | 0.90 | ALDH1A1 (0.49) | DRD2DRD4ALDH1A1PNMTCD44 | |
| Indoline SCHEMBL9132798 | 0.89 | HTR2C (0.50) | DRD2DRD4ALDH1A1PNMTCD44 | |
| Indoline SCHEMBL10798458 | 0.88 | ALDH1A1 (0.43) | DRD2DRD4ALDH1A1PNMTCD44 | |
| Indoline SCHEMBL28177180 | 0.87 | HTR2C (0.48) | DRD2DRD4ALDH1A1PNMTCD44 | |
| Indoline SCHEMBL29360339 | 0.87 | — | — | |
| Indoline SCHEMBL5629 | 0.87 | — | — | |
| Indoline SCHEMBL87372 | 0.85 | HTR2C (0.46) | DRD2DRD4ALDH1A1PNMTCD44 | |
| Indoline SCHEMBL23295083 | 0.85 | HTR2C (0.50) | DRD2DRD4ALDH1A1PNMTCD44 | |
| Indoline SCHEMBL11401846 | 0.85 | HTR2C (0.50) | DRD2DRD4ALDH1A1PNMTCD44 | |
| Indoline SCHEMBL10723456 | 0.85 | HTR2C (0.50) | DRD2DRD4ALDH1A1PNMTCD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009123-A1 | HETEROCYCLIC AMINO-BORANES | BORON BIOLOGICALS, INC. (US) | 1993-05-13 | — | — | WO | claimed |
| US-5280119-A | Heterocyclic amine attached to boron by a nitrogen-boron coordinated bond | BORON BIOLOGICALS, INC. (US) | 1994-01-18 | — | — | US | disclosed |
| WO-1993009123-A1 | HETEROCYCLIC AMINO-BORANES | BORON BIOLOGICALS, INC. (US) | 1993-05-13 | — | — | WO | disclosed |