Indoline

Indoline

SCHEMBL87372

C#N.c1ccc2c(c1)CCN2

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.46
DRD2 P14416 1/20 0.45
DRD4 P21917 1/20 0.45
PDPK1 O15530 1/20 0.45
PARP1 P09874 1/20 0.45
PARP10 Q53GL7 1/20 0.45
PARP11 Q9NR21 1/20 0.45
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 2/20 0.43
NPC1 O15118 1/20 0.42
MAPK13 O15264 1/20 0.42
MAPK12 P53778 1/20 0.42
MAPK11 Q15759 1/20 0.42
MAPK14 Q16539 1/20 0.42
PNMT P11086 1/20 0.41
CD44 P16070 1/20 0.41
MAOB P27338 1/20 0.41
MAPT P10636 2/20 0.39
ALDH1A1 P00352 3/20 0.39
GAA P10253 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indoline SCHEMBL29360339 0.93
Indoline SCHEMBL5629 0.93
Indoline SCHEMBL1085136 0.91 HTR2C (0.50) HTR2CDRD2DRD4PDPK1PARP1
Indoline SCHEMBL10723456 0.91 HTR2C (0.50) HTR2CDRD2DRD4PDPK1PARP1
Indoline SCHEMBL2925258 0.91 HTR2C (0.50) HTR2CDRD2DRD4PDPK1PARP1
Indoline SCHEMBL23295083 0.91 HTR2C (0.50) HTR2CDRD2DRD4PDPK1PARP1
Indoline SCHEMBL11401846 0.91 HTR2C (0.50) HTR2CDRD2DRD4PDPK1PARP1
Indoline SCHEMBL8194348 0.91 HTR2C (0.50) HTR2CDRD2DRD4PDPK1PARP1
Indoline SCHEMBL1587228 0.91 HTR2C (0.50) HTR2CDRD2DRD4PDPK1PARP1
Indoline SCHEMBL4903255 0.91 HTR2C (0.50) HTR2CDRD2DRD4PDPK1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114207055-B Radiation curable intaglio ink 锡克拜控股有限公司 2023-08-25 CN disclosed
CN-114207055-A Radiation curable intaglio ink 锡克拜控股有限公司 2022-03-18 CN disclosed
CN-108330740-B Optically variable security threads and stripes 锡克拜控股有限公司 2020-10-23 CN disclosed
CN-108330740-A Optically-variable safety line and item 锡克拜控股有限公司 2018-07-27 CN disclosed
CN-104704366-B Azaindole quinoline-the cyanine dye and its bioconjugates of hydroxamic acid substitution 贝克顿·迪金森公司 2018-06-19 CN disclosed
CN-105637147-B Optically variable security threads and stripes 锡克拜控股有限公司 2018-04-10 CN disclosed
CN-104837937-B Oxidation drying type ink composite 锡克拜控股有限公司 2018-01-12 CN disclosed
CN-101238141-B The new labelling strategies of sensitive detection of analytes 巴斯福股份公司 2016-10-12 CN disclosed
CN-105637147-A Optically variable security threads and stripes SICPA HOLDING SA 2016-06-01 CN disclosed
CN-104837937-A Oxidatively drying ink compositions SICPA HOLDING SA 2015-08-12 CN disclosed
US-20120107943-A1 Labelling Strategies for the Sensitive Detection of Analytes BASECLICK GMBH (DE) 2012-05-03 US disclosed
US-8129315-B2 Labelling strategies for the sensitive detection of analytes BASECLICK GMBH (DE) 2012-03-06 US disclosed
EP-2270228-A1 New labelling strategies for the sensitive detection of analytes baseclick GmbH (DE) 2011-01-05 EP disclosed
EP-2266996-A2 New labelling strategies for the sensitive detection of analytes baseclick GmbH (DE) 2010-12-29 EP disclosed
EP-2256126-A1 New labelling strategies for the sensitive detection of analytes baseclick GmbH (DE) 2010-12-01 EP disclosed
EP-1877415-B1 NEW LABELLING STRATEGIES FOR THE SENSITIVE DETECTION OF ANALYTES BASECLICK GMBH (DE) 2010-09-01 EP disclosed
US-20090215635-A1 LABELLING STRATEGIES FOR THE SENSITIVE DETECTION OF ANALYTES BASF SE (DE) 2009-08-27 US disclosed
CN-101238141-A New labelling strategies for the sensitive detection of analytes BASF AG (DE) 2008-08-06 CN disclosed
EP-1877415-A2 NEW LABELLING STRATEGIES FOR THE SENSITIVE DETECTION OF ANALYTES BASF AKTIENGESELLSCHAFT (DE) 2008-01-16 EP disclosed
WO-2006117161-A2 NEW LABELLING STRATEGIES FOR THE SENSITIVE DETECTION OF ANALYTES BASF AKTIENGESELLSCHAFT (DE) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215635-A1 LABELLING STRATEGIES FOR THE SENSITIVE DETECTION OF ANALYTES MTREX, ADAR, GUSB HTR2C 4286/4885DRD2 4698/4885DRD4 3518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.