Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400851 | 0.86 | HTR1A (0.53) | KDM1ADRD3DRD2DRD4HTR1A | |
| SCHEMBL9480683 | 0.76 | HTR1A (0.64) | DRD3DRD2DRD4HTR1AHTR2A | |
| SCHEMBL9400965 | 0.74 | HTR1A (0.64) | DRD3DRD2DRD4HTR1AHTR2A | |
| SCHEMBL9400884 | 0.70 | DRD2 (0.39) | DRD3DRD2DRD4HTR1AHTR2A | |
| SCHEMBL9401031 | 0.70 | HTR1A (0.95) | DRD3DRD2DRD4HTR1AHTR2A | |
| SCHEMBL14762044 | 0.69 | DRD2 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL9286378 | 0.68 | LMNA (0.59) | DRD3DRD2HTR1AHTR2A | |
| SCHEMBL9401029 | 0.68 | HTR1A (0.68) | DRD3DRD2DRD4HTR1AHTR2A | |
| SCHEMBL6866193 | 0.68 | DRD2 (0.74) | DRD3DRD2DRD4HTR1AHTR2A | |
| SCHEMBL10565838 | 0.67 | DRD2 (0.44) | DRD3DRD2DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314884-A | Antidepressants, anxiolytic agents | TROPONWERKE GMBH & CO. (DE) | 1994-05-24 | — | — | US | disclosed |
| US-4818756-A | CENTRAL NERVOUS SYSTEM DISORDERS | TROPONWERKE GMBH & CO., KG (DE) | 1989-04-04 | — | — | US | disclosed |