Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.51 |
| ▸ | GPX4 | P36969 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 3/20 | 0.43 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481710 | 0.82 | TRPV1 (0.45) | BAZ2BLMNAMAPTTRPV1GPX4 | |
| SCHEMBL2724003 | 0.79 | LMNA (0.80) | BAZ2BLMNAMAPTTRPV1GPX4 | |
| SCHEMBL6473473 | 0.78 | LMNA (0.44) | BAZ2BLMNAMAPTTRPV1CDK4 | |
| SCHEMBL6475935 | 0.77 | PARP1 (0.43) | BAZ2BLMNAMAPTTRPV1 | |
| SCHEMBL4008584 | 0.74 | NOTUM (0.61) | BAZ2BLMNAMAPT | |
| SCHEMBL11499238 | 0.73 | BAZ2B (0.52) | BAZ2BLMNAMAPTTRPV1CDK4 | |
| SCHEMBL5373325 | 0.73 | GPX4 (0.49) | TRPV1GPX4FAAHCDK4CCND1 | |
| SCHEMBL5376729 | 0.73 | CDK4 (0.54) | TRPV1GPX4FAAHCDK4CCND1 | |
| SCHEMBL1000958 | 0.71 | LMNA (0.71) | BAZ2BLMNAMAPTTRPV1GPX4 | |
| SCHEMBL12269322 | 0.71 | NOTUM (0.61) | BAZ2BLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314908-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5206377-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1993-04-27 | — | — | US | disclosed |