SCHEMBL9401252

SCHEMBL9401252

COc1cc(OC)nc(SC(C=O)c2ccccc2C)n1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTSA P10619 4/20 0.43
ESR1 P03372 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9401303 0.86 CTSA (0.34) CTSAALDH1A1
SCHEMBL9401207 0.85 NPC1 (0.34) CTSAALDH1A1
SCHEMBL9401279 0.85 NPSR1 (0.37) CTSA
SCHEMBL9401531 0.85 EDNRB (0.37) CTSAALDH1A1
SCHEMBL9401364 0.83 CTSA (0.41) CTSAESR1
SCHEMBL9401440 0.82 PTGES (0.40)
SCHEMBL9572237 0.78 EDNRB (0.36) ALDH1A1
SCHEMBL9401323 0.77 EDNRB (0.37)
SCHEMBL9401347 0.77 MEN1 (0.39)
SCHEMBL9401325 0.76 HTT (0.36) CTSAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5346880-A Pre- and postemergence NIHON BAYER AGROCHEM K.K. (JP) 1994-09-13 US disclosed
EP-0565951-A1 Herbicidally active pyrimidinylthioalkane derivatives NIHON BAYER AGROCHEM K.K. (JP) 1993-10-20 EP disclosed