SCHEMBL9401416

SCHEMBL9401416

COC(=O)C(Sc1nc(OC)cc(OC)n1)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 1/20 0.41
ADORA3 P0DMS8 2/20 0.41
ADORA1 P30542 1/20 0.40
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9562993 0.86 CYP1A2 (0.41) CYP1A2ALDH1A1KDM4EADORA3ADORA1
SCHEMBL16160330 0.86 CYP1A2 (0.44) CYP1A2ALDH1A1KDM4EADORA3ADORA1
SCHEMBL9082975 0.86 ALOX5 (0.44) CYP1A2ALDH1A1KDM4E
SCHEMBL13851482 0.86 ALOX5 (0.44) CYP1A2ALDH1A1KDM4E
SCHEMBL13851483 0.86 ALOX5 (0.44) CYP1A2ALDH1A1KDM4E
SCHEMBL9562994 0.85 CYP1A2 (0.41) CYP1A2ALDH1A1KDM4EADORA3ADORA1
SCHEMBL9562977 0.81 ADORA3 (0.45) CYP1A2ALDH1A1KDM4EADORA3ADORA1
SCHEMBL9562995 0.81 CYP1A2 (0.36) CYP1A2ALDH1A1KDM4EADORA3ADORA1
SCHEMBL9755676 0.80 PPARA (0.47) CYP1A2ALDH1A1KDM4EADORA3ADORA1
SCHEMBL7936610 0.80 KMT2A (0.43) ADORA3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5346880-A Pre- and postemergence NIHON BAYER AGROCHEM K.K. (JP) 1994-09-13 US disclosed
EP-0565951-A1 Herbicidally active pyrimidinylthioalkane derivatives NIHON BAYER AGROCHEM K.K. (JP) 1993-10-20 EP disclosed