SCHEMBL9562977

SCHEMBL9562977

CCOC(OCC)C(Sc1nc(OC)cc(OC)n1)C(=O)OC

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 0.45
ADORA1 P30542 1/20 0.44
ALDH1A1 P00352 3/20 0.38
CYP1A2 P05177 1/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9562993 0.86 CYP1A2 (0.41) ADORA3ADORA1ALDH1A1CYP1A2KDM4E
SCHEMBL9562979 0.83 ADORA3 (0.44) ADORA3ADORA1ALDH1A1CYP1A2KDM4E
SCHEMBL9401416 0.81 CYP1A2 (0.42) ADORA3ADORA1ALDH1A1CYP1A2KDM4E
SCHEMBL9562994 0.79 CYP1A2 (0.41) ADORA3ADORA1ALDH1A1CYP1A2KDM4E
SCHEMBL9562980 0.76 ADORA3 (0.42) ADORA3ADORA1ALDH1A1KDM4EMAPT
SCHEMBL7936610 0.75 KMT2A (0.43) ADORA3MAPT
SCHEMBL9589280 0.74 ADORA3 (0.41) ADORA3ADORA1ALDH1A1KDM4EMAPT
SCHEMBL9408702 0.74 ALOX5 (0.43) ADORA3ADORA1
SCHEMBL9706622 0.73 ALDH1A1 (0.43) ADORA3ADORA1ALDH1A1KDM4EMAPT
SCHEMBL9401283 0.73 ALOX5 (0.59) ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573837-A1 Acetal-containing pyrimidinylthioaliphatic acid derivatives useful as herbicides NIHON BAYER AGROCHEM K.K. (JP) 1993-12-15 EP claimed
EP-0573837-A1 Acetal-containing pyrimidinylthioaliphatic acid derivatives useful as herbicides NIHON BAYER AGROCHEM K.K. (JP) 1993-12-15 EP disclosed