SCHEMBL9401526

SCHEMBL9401526

CCC(CO)Sc1nc(OC)cc(OC)n1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
ADORA3 P0DMS8 2/20 0.38
ALOX5 P09917 2/20 0.37
PPARG P37231 2/20 0.37
PTGES O14684 1/20 0.37
ADORA1 P30542 1/20 0.37
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9401391 0.89 ADORA3 (0.38) ALDH1A1ADORA3ALOX5PPARGPTGES
SCHEMBL9401547 0.86 ALOX5 (0.44) ADORA3ALOX5PPARGPTGES
SCHEMBL9401363 0.85 ALDH1A1 (0.36) ALDH1A1ADORA3ADORA1CYP1A2
SCHEMBL9401293 0.85 ALDH1A1 (0.36) ALDH1A1ALOX5PPARG
SCHEMBL9401619 0.85 ALOX5 (0.41) ADORA3ALOX5PPARGPTGESADORA1
SCHEMBL9401209 0.84 ALDH1A1 (0.35) ALDH1A1ADORA3ALOX5PPARGPTGES
SCHEMBL9401194 0.84 ALOX5 (0.40) ALDH1A1ADORA3ALOX5PPARGPTGES
SCHEMBL9401275 0.84 ALDH1A1 (0.35) ALDH1A1ADORA3ALOX5PPARGPTGES
SCHEMBL9401317 0.84 ALOX5 (0.43) ADORA3ALOX5PPARGPTGESADORA1
SCHEMBL9401336 0.84 ALOX5 (0.43) ADORA3ALOX5PPARGPTGESADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5346880-A Pre- and postemergence NIHON BAYER AGROCHEM K.K. (JP) 1994-09-13 US disclosed
EP-0593998-A1 Pyrimidinylthioalkane herbicides NIHON BAYER AGROCHEM K.K. (JP) 1994-04-27 EP disclosed
EP-0565951-A1 Herbicidally active pyrimidinylthioalkane derivatives NIHON BAYER AGROCHEM K.K. (JP) 1993-10-20 EP disclosed