Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27566517 | 0.90 | CACNA1B (0.62) | CACNA1BADORA2BCYP1A2CYP2C9MAPK1 | |
| SCHEMBL6951320 | 0.81 | ADORA3 (0.76) | CACNA1BADORA3TSHRKDM4EHSD17B10 | |
| SCHEMBL3010290 | 0.81 | ADORA2B (0.67) | CACNA1BADORA3TSHRKDM4EHSD17B10 | |
| SCHEMBL7265410 | 0.80 | TSHR (0.65) | CACNA1BADORA3TSHRKDM4EHSD17B10 | |
| SCHEMBL27520045 | 0.80 | CACNA1B (0.65) | CACNA1BTSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7158395 | 0.79 | ADORA3 (0.60) | CACNA1BADORA3TSHRKDM4EHSD17B10 | |
| SCHEMBL5857481 | 0.78 | CACNA1B (1.00) | CACNA1B | |
| SCHEMBL5857475 | 0.78 | CACNA1B (1.00) | CACNA1B | |
| SCHEMBL9401767 | 0.78 | KDM4E (0.68) | ADORA3TSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9272854 | 0.78 | CACNA1F (0.69) | CACNA1BADORA3TSHRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |