Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817128 | 0.94 | KDM4E (0.76) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7815188 | 0.93 | ALDH1A1 (0.68) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9401767 | 0.89 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL8340560 | 0.86 | CACNA1F (0.69) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11822298 | 0.84 | HSD17B10 (0.61) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7436006 | 0.82 | TSHR (0.72) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL28735886 | 0.81 | ALDH1A1 (0.62) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9064391 | 0.81 | ADORA3 (0.78) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL7814802 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL16137718 | 0.80 | TSHR (0.70) | KDM4EALDH1A1HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100028912-A1 | IMAGING USING RADIOACTIVE MONOCATIONS IN COMBINATION WITH A RECEPTOR BINDING LIGAND THAT STIMULATES THE INFLUX OF CATIONS | BRACCO IMAGING S.P.A. (IT) | 2010-02-04 | — | — | US | disclosed |
| EP-2121037-A2 | IMAGING USING RADIOACTIVE MONOCATIONS IN COMBINATION WITH A RECEPTOR BINDING LIGAND THAT STIMULATES THE INFLUX OF CATIONS | BRACCO IMAGING S.p.A. (IT) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008082545-A2 | IMAGING USING RADIOACTIVE MONOCATIONS IN COMBINATION WITH A RECEPTOR BINDING LIGAND THAT STIMULATES THE INFLUX OF CATIONS | BRACCO IMAGING S.P.A. (IT) | 2008-07-10 | — | — | WO | disclosed |