Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | PYGM | P11217 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | DDO | Q99489 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11667144 | 0.72 | HDAC8 (0.42) | BRD4CA12CA1CA3CA4 | |
| SCHEMBL21408183 | 0.71 | BRD4 (0.44) | BRD4LMNACA12CA1CA3 | |
| SCHEMBL6985477 | 0.70 | DAO (0.46) | BRD4CA12CA1CA3CA4 | |
| SCHEMBL3915457 | 0.70 | BRD4 (0.42) | BRD4LMNAHRH4CA12CA1 | |
| SCHEMBL77736 | 0.70 | LMNA (0.61) | BRD4LMNA | |
| SCHEMBL9880049 | 0.70 | ALOX5 (0.43) | BRD4PYGLPYGMLMNAHRH4 | |
| SCHEMBL7203954 | 0.69 | HRH4 (0.53) | HRH4CHRNA7 | |
| SCHEMBL5584506 | 0.68 | AOC3 (0.40) | CA12CA1CA3CA4CA6 | |
| SCHEMBL73543 | 0.68 | AOC3 (0.47) | BRD4CA12CA1CA3CA4 | |
| SCHEMBL6155692 | 0.67 | HRH4 (0.42) | HRH4KDRCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338859-A | Reacting a hydantoin with a calcium base; crystallization; precipitation; separation | HOECHST CELANESE CORPORATION (US) | 1994-08-16 | — | — | US | claimed |
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | claimed |
| US-5338859-A | Reacting a hydantoin with a calcium base; crystallization; precipitation; separation | HOECHST CELANESE CORPORATION (US) | 1994-08-16 | — | — | US | disclosed |
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | disclosed |