Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402210 | 0.88 | AGTR1 (0.54) | AGTR1 | |
| SCHEMBL9402481 | 0.87 | AGTR1 (0.70) | AGTR1 | |
| SCHEMBL9402273 | 0.86 | — | — | |
| SCHEMBL9402218 | 0.82 | AGTR1 (0.64) | AGTR1 | |
| SCHEMBL9402392 | 0.81 | ALDH1A1 (0.52) | — | |
| SCHEMBL9402219 | 0.80 | — | — | |
| SCHEMBL9402502 | 0.79 | AGTR1 (0.79) | AGTR1 | |
| SCHEMBL9402274 | 0.79 | — | — | |
| SCHEMBL9402246 | 0.77 | ALDH1A1 (0.51) | — | |
| SCHEMBL9402244 | 0.77 | AGTR1 (0.63) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |