⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402287 | 0.91 | LMNA (0.51) | — | |
| SCHEMBL9402365 | 0.85 | TLR7 (0.50) | — | |
| SCHEMBL9402270 | 0.84 | ALDH1A1 (0.67) | — | |
| SCHEMBL9402239 | 0.82 | ALDH1A1 (0.46) | — | |
| SCHEMBL9402189 | 0.80 | AGTR1 (0.68) | — | |
| SCHEMBL9402206 | 0.80 | AGTR1 (0.57) | — | |
| SCHEMBL11511765 | 0.79 | NPC1 (0.53) | — | |
| SCHEMBL7409233 | 0.79 | HTT (0.51) | — | |
| SCHEMBL9402500 | 0.78 | AGTR1 (0.57) | — | |
| SCHEMBL9402209 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |