Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402284 | 0.91 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9402185 | 0.90 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9402316 | 0.88 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9402208 | 0.85 | — | — | |
| SCHEMBL9402484 | 0.82 | — | — | |
| SCHEMBL9402514 | 0.81 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9402396 | 0.81 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9402252 | 0.81 | AGTR1 (0.53) | AGTR1 | |
| SCHEMBL9402199 | 0.80 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL3347424 | 0.79 | GP6 (0.53) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | claimed |
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |