Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402215 | 0.91 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9402185 | 0.87 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9402504 | 0.86 | — | — | |
| SCHEMBL9402316 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9402384 | 0.82 | — | — | |
| SCHEMBL9195684 | 0.79 | EDNRA (0.55) | AGTR1AGTR2 | |
| SCHEMBL9199706 | 0.79 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9402514 | 0.79 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9033783 | 0.78 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9402301 | 0.78 | AGTR1 (0.49) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | claimed |
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |