Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402203 | 0.84 | ALDH1A1 (0.45) | LMNAADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL9402286 | 0.80 | POLB (0.43) | LMNAPOLBTLR7ACHE | |
| SCHEMBL9402176 | 0.79 | TLR7 (0.47) | TLR7ACHEMEN1KMT2A | |
| SCHEMBL9402257 | 0.75 | — | — | |
| SCHEMBL4442256 | 0.74 | ALDH1A1 (0.78) | LMNAPOLBNPC1ALDH1A1TSHR | |
| SCHEMBL9402406 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9402270 | 0.73 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9402501 | 0.72 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL9402388 | 0.71 | ALDH1A1 (0.56) | LMNAALDH1A1 | |
| SCHEMBL9699713 | 0.70 | TLR7 (0.53) | TLR7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |