Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402286 | 0.81 | POLB (0.43) | TLR7ACHEL3MBTL1 | |
| SCHEMBL9402388 | 0.81 | ALDH1A1 (0.56) | — | |
| SCHEMBL9402501 | 0.79 | ALDH1A1 (0.47) | — | |
| SCHEMBL9402406 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2A | |
| SCHEMBL9402270 | 0.79 | ALDH1A1 (0.67) | — | |
| SCHEMBL9402222 | 0.79 | LMNA (0.49) | TLR7ACHEMEN1KMT2A | |
| SCHEMBL7412061 | 0.78 | ALDH1A1 (0.55) | — | |
| SCHEMBL277 | 0.77 | AGTR1 (0.60) | AGTR1 | |
| SCHEMBL7320199 | 0.77 | TLR7 (0.48) | TLR7ACHEMEN1KMT2AAGTR1 | |
| SCHEMBL649 | 0.77 | AGTR1 (0.58) | TLR7AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |