Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402256 | 0.82 | KDM4E (0.45) | TLR7KDM4E | |
| SCHEMBL9402176 | 0.81 | TLR7 (0.47) | TLR7ACHEL3MBTL1 | |
| SCHEMBL9402222 | 0.80 | LMNA (0.49) | POLBTLR7ACHELMNA | |
| SCHEMBL9402406 | 0.76 | ALDH1A1 (0.49) | — | |
| SCHEMBL9402501 | 0.74 | ALDH1A1 (0.47) | — | |
| SCHEMBL9402388 | 0.73 | ALDH1A1 (0.56) | LMNA | |
| SCHEMBL9402270 | 0.73 | ALDH1A1 (0.67) | — | |
| SCHEMBL28489677 | 0.72 | PDE6D (0.56) | LMNANPSR1 | |
| SCHEMBL7412061 | 0.72 | ALDH1A1 (0.55) | LMNA | |
| SCHEMBL9402379 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |