Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402219 | 0.91 | — | — | |
| SCHEMBL7409233 | 0.88 | HTT (0.51) | LMNAHSP90AA1HTTALDH1A1TP53 | |
| SCHEMBL9402388 | 0.84 | ALDH1A1 (0.56) | LMNAHTTALDH1A1TP53MAPT | |
| SCHEMBL9402239 | 0.82 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL9402495 | 0.79 | AGTR1 (0.51) | — | |
| SCHEMBL9402349 | 0.78 | AGTR1 (0.65) | — | |
| SCHEMBL9402392 | 0.78 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL9402246 | 0.78 | ALDH1A1 (0.51) | HTTALDH1A1MAPT | |
| SCHEMBL9402365 | 0.78 | TLR7 (0.50) | — | |
| SCHEMBL9402252 | 0.77 | AGTR1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |