Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402199 | 0.82 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9402495 | 0.80 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9448503 | 0.79 | PPARG (0.57) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9402474 | 0.77 | PPARG (0.55) | PPARGACHE | |
| SCHEMBL9402289 | 0.76 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL3459616 | 0.74 | PPARG (0.59) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9198282 | 0.74 | PPARG (0.70) | PPARGAGTR1AGTR2 | |
| SCHEMBL9194096 | 0.74 | PPARG (0.70) | PPARGAGTR1AGTR2 | |
| SCHEMBL12716740 | 0.74 | PPARG (0.61) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL6430 | 0.74 | PPARG (0.61) | PPARGACHEAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |