Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402495 | 0.86 | AGTR1 (0.51) | — | |
| SCHEMBL9448503 | 0.85 | PPARG (0.57) | PPARGACHE | |
| SCHEMBL9402340 | 0.83 | PPARG (0.47) | PPARGACHE | |
| SCHEMBL9402197 | 0.82 | ALDH1A1 (0.51) | — | |
| SCHEMBL9843750 | 0.79 | PPARG (0.56) | PPARGACHE | |
| SCHEMBL9402357 | 0.79 | AGTR1 (0.49) | — | |
| SCHEMBL3459616 | 0.78 | PPARG (0.59) | PPARGACHE | |
| SCHEMBL9197325 | 0.78 | PPARG (0.88) | PPARG | |
| SCHEMBL12716740 | 0.78 | PPARG (0.61) | PPARGACHE | |
| SCHEMBL6430 | 0.78 | PPARG (0.61) | PPARGACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |