Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402795 | 0.81 | TDP1 (0.39) | MLYCDNR1H4MAPTNPC1 | |
| SCHEMBL25137571 | 0.80 | MLYCD (0.43) | MLYCDHDAC1HDAC6MAPTNPC1 | |
| SCHEMBL9184350 | 0.80 | MAPT (0.44) | MLYCDHDAC1MAPTNPC1RAB9A | |
| SCHEMBL9402592 | 0.79 | MLYCD (0.42) | MLYCDHDAC1MAPTNPC1RAB9A | |
| SCHEMBL27920780 | 0.79 | ALDH1A1 (0.55) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5390967 | 0.78 | ALDH1A1 (0.55) | HDAC1HDAC3HDAC8HDAC6MAPT | |
| SCHEMBL28796093 | 0.77 | CA1 (0.62) | MAPTNPC1RAB9ASMN1; SMN2CA1 | |
| SCHEMBL23921254 | 0.76 | MLYCD (0.40) | MLYCDHDAC1HDAC6MAPTNPC1 | |
| SCHEMBL9781221 | 0.76 | MPO (0.57) | MLYCDHDAC1HDAC6MAPTCA1 | |
| SCHEMBL9402921 | 0.75 | MLYCD (0.35) | MLYCDHDAC1HDAC3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |