SCHEMBL940286

SCHEMBL940286

Cc1cc(N)cc(C)c1Cc1c(C)cc(N)cc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
TSHR P16473 4/20 0.45
ALOX15 P16050 2/20 0.39
CYP1A2 P05177 1/20 0.39
CASP7 P55210 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PDE10A Q9Y233 1/20 0.39
CASP1 P29466 2/20 0.36
CYP3A4 P08684 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPK1 P28482 1/20 0.35
TP53 P04637 1/20 0.35
HTR1D P28221 3/20 0.34
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30259832 0.81 NOS3 (0.39) ALDH1A1TSHRALOX15CYP1A2CASP7
SCHEMBL1004953 0.81 NOS3 (0.39) ALDH1A1TSHRALOX15CYP1A2CASP7
SCHEMBL11412026 0.80 ALDH1A1 (0.43) ALDH1A1TSHRALOX15CYP1A2CASP7
SCHEMBL17442579 0.80 ALDH1A1 (0.43) ALDH1A1TSHRALOX15CYP1A2CASP7
SCHEMBL8096035 0.79 GFER (0.46) ALDH1A1TSHRCYP3A4TDP1THRB
SCHEMBL6739111 0.78 ALDH1A1 (0.41) ALDH1A1TSHRALOX15CYP1A2CASP7
SCHEMBL28298449 0.78 HTR1D (0.41) ALDH1A1TSHRPDE10ACASP1HTR1D
SCHEMBL8100135 0.76 MAOB (0.44) ALDH1A1TSHRALOX15HSD17B10CYP3A4
SCHEMBL3985532 0.76 HSP90AB1 (0.43) ALDH1A1TSHRCYP3A4TDP1MEN1
SCHEMBL8100324 0.76 SKP2 (0.42) ALDH1A1TSHRCYP3A4TDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6067139-A SUPER TWISTED NEMATIC LIQUID CRYSTAL DISPLAY (STN LCD), HAVING AT LEAST TWO DOMAINS PER PIXEL, (MULTI-DOMAIN STN LCDS), USING A FLUORINATED POLYIMIDE ALIGNMENT FILM WHICH MAINTAINS A STABLE TILT ANGLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-23 US claimed
WO-2025235535-A2 FUNCTIONALIZED POROUS POLYMER NETWORKS FOR PER- AND/OR POLY-FLUOROALKYL BINDING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-11-13 WO disclosed
US-20250214042-A1 MEMBRANES INCORPORATED WITH POROUS POLYMER FRAMEWORKS U.S. DEPARTMENT OF ENERGY 2025-07-03 US disclosed
WO-2025080654-A1 MULTI-FUNCTIONAL FILTRATION SYSTEMS FOR METAL AND OXYANION REMOVAL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-04-17 WO disclosed
US-12157094-B2 Gas separation method with multilayer membrane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-12-03 US disclosed
US-12138596-B2 Method for separating carbon dioxide and methane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-11-12 US disclosed
US-12138597-B2 Method for making and using a gas separation membrane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-11-12 US disclosed
US-12109539-B2 Membrane permeation gas separation method KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-08 US disclosed
US-12102967-B2 Method for separating a gas stream to isolate carbon dioxide KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-01 US disclosed
US-12102966-B2 CO2 gas enrichment method KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-01 US disclosed
EP-0758000-A2 Polyimide films from pyromellitic dianhydride and 2,2'-bis(perfluoroalkoxy)benzidines as alignment layers for liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-02-12 EP disclosed
US-5426172-A Semipermeable membranes CIBA-GEIGY CORPORATION (US) 1995-06-20 US disclosed
US-5322922-A Used fo rprotective layers or relief images CIBA-GEIGY CORPORATION (US) 1994-06-21 US disclosed
US-5198119-A Semipermeable Membranes CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed
EP-0473541-A2 Process for enrichment or separation, copolyamide and copolyimidamide and their use CIBA-GEIGY AG (CH) 1992-03-04 EP disclosed
EP-0368932-A4 POLYISOCYANATE COMPOSITIONS CONTAINING RIGID COMPOUNDS OR POLYMERS, AND POLYURETHANES PREPARED THEREFROM 1990-09-05 EP disclosed
EP-0368932-A1 POLYISOCYANATE COMPOSITIONS CONTAINING RIGID COMPOUNDS OR POLYMERS, AND POLYURETHANES PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1990-05-23 EP disclosed
US-4894403-A USING ETHYLENICALLY UNSATURATED AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1990-01-16 US disclosed
EP-0302271-A1 Polyisocyanate compositions containing rigid compounds or polymers, and polyurethanes prepared therefrom THE DOW CHEMICAL COMPANY (US) 1989-02-08 EP disclosed
WO-1989000597-A1 POLYISOCYANATE COMPOSITIONS CONTAINING RIGID COMPOUNDS OR POLYMERS, AND POLYURETHANES PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1989-01-26 WO disclosed