SCHEMBL1004953

SCHEMBL1004953

CCc1cc(N)cc(C)c1Cc1c(C)cc(N)cc1CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.39
NOS2 P35228 2/20 0.39
NOS1 P29475 1/20 0.39
ALDH1A1 P00352 5/20 0.35
CYP1A2 P05177 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP7 P55210 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TSHR P16473 1/20 0.35
DHFR P00374 1/20 0.34
HTT P42858 2/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
POLB P06746 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
THRA P10827 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30259832 1.00 NOS3 (0.39) NOS3NOS2NOS1ALDH1A1CYP1A2
SCHEMBL20012880 0.89 NOS3 (0.41) NOS3NOS2NOS1ALDH1A1CYP1A2
SCHEMBL2031885 0.86 DHFR (0.38) NOS3NOS2NOS1ALDH1A1CYP1A2
SCHEMBL940286 0.81 ALDH1A1 (0.45) ALDH1A1CYP1A2ALOX15CASP7HIF1A
SCHEMBL396696 0.79 DHFR (0.43) NOS3NOS2NOS1ALDH1A1TSHR
SCHEMBL11412026 0.79 ALDH1A1 (0.43) NOS3NOS2NOS1ALDH1A1CYP1A2
SCHEMBL12964261 0.77 NOS3 (0.42) NOS3NOS2NOS1ALDH1A1CYP1A2
SCHEMBL5158799 0.77 ALDH1A1 (0.52) NOS3NOS2NOS1ALDH1A1CYP1A2
SCHEMBL17058864 0.76 IMPDH2 (0.33) NOS3NOS2NOS1CYP1A2ALOX15
SCHEMBL7601632 0.76 ALDH1A1 (0.46) NOS3NOS2NOS1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12077644-B2 Amide acid oligomer process for molding polyimide composites KANEKA AMERICAS HOLDING, INC. (US) 2024-09-03 US claimed
CN-112888726-B Novel amic acid oligomer process for molding polyimide composites 钟化美洲控股公司 2023-10-03 CN claimed
US-20210340344-A1 Novel Amide Acid Oligomer Process For Molding Polyimide Composites KANEKA AMERICAS HOLDING, INC. (US) 2021-11-04 US claimed
EP-3841152-A1 A NOVEL AMIDE ACID OLIGOMER PROCESS FOR MOLDING POLYIMIDE COMPOSITES Kaneka Americas Holding, Inc. (US) 2021-06-30 EP claimed
CN-112888726-A Novel amic acid oligomer process for molding polyimide composites 钟化美洲控股公司 2021-06-01 CN claimed
US-10815390-B2 Polyimide resin composition and varnish produced from terminal-modified imide oligomer prepared using 2-phenyl-4,4′-diaminodiphenyl ether and thermoplastic aromatic polyimide prepared using oxydiphthalic acid, polyimide resin composition molded article and prepreg having excellent heat resistance and mechanical characteristic, and fiber-reinforced composite material thereof KANEKA CORPORATION (JP) 2020-10-27 US claimed
WO-2020072639-A1 A NOVEL AMIDE ACID OLIGOMER PROCESS FOR MOLDING POLYIMIDE COMPOSITES KANEKA AMERICAS HOLDING, INC. (US) 2020-04-09 WO claimed
US-20180273798-A1 POLYIMIDE RESIN COMPOSITION AND VARNISH PRODUCED FROM TERMINAL-MODIFIED IMIDE OLIGOMER PREPARED USING 2-PHENYL-4,4'-DIAMINODIPHENYL ETHER AND THERMOPLASTIC AROMATIC POLYIMIDE PREPARED USING OXYDIPHTHALIC ACID, POLYIMIDE RESIN COMPOSITION MOLDED ARTICLE AND PREPREG HAVING EXCELLENT HEAT RESISTANCE AND MECHANICAL CHARACTERISTIC, AND FIBER-REINFORCED COMPOSITE MATERIAL THEREOF KANEKA CORPORATION (JP) 2018-09-27 US claimed
US-10017666-B2 Polyimide resin composition and varnish produced from terminal-modified imide oligomer prepared using 2-phenyl-4,4′-diaminodiphenyl ether and thermoplastic aromatic polyimide prepared using oxydiphthalic acid, polyimide resin composition molded article and prepreg having excellent heat resistance and mechanical characteristic, and fiber-reinforced composite material thereof KANEKA CORPORATION (JP) 2018-07-10 US claimed
US-12590184-B2 Polyimide resin molded body and production method for same TOYO SEIKAN GROUP HOLDINGS, LTD. (JP) 2026-03-31 US disclosed
EP-3892672-B1 FIBER-REINFORCED POLYIMIDE RESIN MOLDING PRECURSOR AND METHOD FOR PRODUCING SAME TOYO SEIKAN GROUP HOLDINGS LTD (JP) 2025-06-25 EP disclosed
US-12305003-B2 Polyamic acid having specific composition, varnish, cured product, and composite material KANEKA CORPORATION (JP) 2025-05-20 US disclosed
US-12221517-B2 Fiber-reinforced polyimide resin molding precursor and method for producing the same TOYO SEIKAN GROUP HOLDINGS, LTD. (JP) 2025-02-11 US disclosed
US-12077644-B2 Amide acid oligomer process for molding polyimide composites KANEKA AMERICAS HOLDING, INC. (US) 2024-09-03 US disclosed
EP-0379131-A2 Thermosetting resin composition UBE INDUSTRIES, LTD. (JP) 1990-07-25 EP disclosed
EP-0371154-A1 Prepreg of reinforced imide oligomer UBE INDUSTRIES, LTD. (JP) 1990-06-06 EP disclosed
US-4921745-A Honeycomb structure of aromatic polyimide UBE INDUSTRIES, LTD. (JP) 1990-05-01 US disclosed
EP-0357367-A2 Terminal-modified aromatic imide oligomer composition UBE INDUSTRIES, LTD. (JP) 1990-03-07 EP disclosed
EP-0304913-A2 Terminal-modified imide oligomer and solution composition of the same UBE INDUSTRIES, LTD. (JP) 1989-03-01 EP disclosed
EP-0254230-A2 Heat-resistant photoresist film Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590184-B2 Polyimide resin molded body and production method for same PBRM1, FGB, PF4 NOS3 2816/4885NOS2 2580/4885NOS1 2778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.