Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402900 | 0.78 | THRB (0.39) | THRBMEN1KMT2ATP53KDM4E | |
| SCHEMBL25959618 | 0.74 | THRB (0.33) | THRBMEN1KMT2ATP53KDM4E | |
| SCHEMBL27503073 | 0.70 | TP53 (0.52) | THRBTP53KDM4EGMNNLMNA | |
| SCHEMBL4298582 | 0.69 | TP53 (0.56) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL3675184 | 0.69 | THRB (0.43) | THRBMEN1KMT2ATP53 | |
| SCHEMBL5709662 | 0.65 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL21811004 | 0.64 | — | — | |
| SCHEMBL9767434 | 0.64 | — | — | |
| SCHEMBL24355461 | 0.64 | THRB (0.38) | THRBMEN1KMT2A | |
| SCHEMBL22081840 | 0.64 | THRB (0.38) | THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236805-B1 | A method for the determination of a nucleic acid using a control | ROCHE DIAGNOSTICS GMBH (DE) | 2008-05-07 | — | — | EP | disclosed |