Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402803 | 0.81 | RAB9A (0.40) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL9402780 | 0.75 | ALDH1A1 (0.41) | — | |
| SCHEMBL9402931 | 0.71 | RAB9A (0.48) | — | |
| SCHEMBL9402628 | 0.70 | ELANE (0.36) | — | |
| SCHEMBL9359357 | 0.69 | MAP2K1 (0.38) | MAP2K1MAP2K2MAP2K5 | |
| SCHEMBL23682944 | 0.69 | LMNA (0.44) | MAPK1 | |
| SCHEMBL9402813 | 0.68 | ELANE (0.33) | — | |
| SCHEMBL9402901 | 0.68 | ELANE (0.36) | MAPK1 | |
| SCHEMBL9402914 | 0.67 | RAB9A (0.50) | — | |
| SCHEMBL9402922 | 0.66 | RAB9A (0.69) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |