Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690766 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTGAAKMT2AHPGD | |
| SCHEMBL7500457 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKMT2AHPGD | |
| SCHEMBL12479803 | 0.82 | CYP19A1 (0.51) | ALDH1A1MAPTTSHR | |
| SCHEMBL5176551 | 0.75 | GAA (0.56) | ALDH1A1MAPTGAAKMT2AHPGD | |
| SCHEMBL5176559 | 0.75 | GAA (0.59) | ALDH1A1MAPTGAAKMT2AHPGD | |
| SCHEMBL9403358 | 0.74 | GAA (0.58) | ALDH1A1MAPTGAAKMT2AHPGD | |
| SCHEMBL7802681 | 0.72 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL3087061 | 0.71 | GAA (0.73) | ALDH1A1MAPTGAAKMT2AHPGD | |
| SCHEMBL8013057 | 0.70 | HPGD (0.44) | ALDH1A1KMT2AHPGDTSHRLMNA | |
| SCHEMBL4220537 | 0.70 | KMT2A (0.55) | GAAKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321139-A | Amination of phenylitaconic anhydride, catalytic reduction of formed amide; renin inhibitor | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-14 | — | — | US | disclosed |