Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175379 | 0.87 | TXNRD1 (0.54) | GAAKMT2AMEN1TXNRD1ALDH1A1 | |
| SCHEMBL5176559 | 0.87 | GAA (0.59) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL5176551 | 0.84 | GAA (0.56) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL5176555 | 0.84 | TXNRD1 (0.51) | GAAKMT2AMEN1TXNRD1ALDH1A1 | |
| SCHEMBL5698188 | 0.84 | TXNRD1 (0.54) | GAAKMT2AMEN1TXNRD1ALDH1A1 | |
| SCHEMBL3087061 | 0.82 | GAA (0.73) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL24323271 | 0.82 | ALDH1A1 (0.56) | GAAKMT2AMEN1TXNRD1ALDH1A1 | |
| SCHEMBL1269639 | 0.82 | CYP1A2 (0.56) | GAAKMT2AMEN1TXNRD1ALDH1A1 | |
| SCHEMBL24584925 | 0.82 | TXNRD1 (0.52) | GAAKMT2AMEN1TXNRD1ALDH1A1 | |
| SCHEMBL553682 | 0.82 | TXNRD1 (0.56) | GAAKMT2AMEN1TXNRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321139-A | Amination of phenylitaconic anhydride, catalytic reduction of formed amide; renin inhibitor | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-14 | — | — | US | disclosed |