Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9403359 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAKMT2AHPGD | |
| SCHEMBL12479803 | 0.83 | CYP19A1 (0.51) | ALDH1A1MAPTTSHR | |
| SCHEMBL7500457 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKMT2AHPGD | |
| SCHEMBL7802681 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL2922871 | 0.76 | NPC1 (0.59) | ALDH1A1GAAKMT2AHPGDMEN1 | |
| SCHEMBL29016375 | 0.76 | ACE (0.44) | TSHRNPSR1 | |
| SCHEMBL3087061 | 0.75 | GAA (0.73) | ALDH1A1MAPTGAAKMT2AHPGD | |
| SCHEMBL4220537 | 0.74 | KMT2A (0.55) | GAAKMT2AMEN1TSHR | |
| SCHEMBL16053132 | 0.74 | GABBR2 (0.43) | GAASLC1A1TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL4205714 | 0.73 | KMT2A (0.54) | GAAKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738803-A | ENZYME INHIBITORS | ROQUES BERNARD (FR) | 1988-04-19 | — | — | US | disclosed |
| US-4618708-A | ENKEPHALINASE INHIBITOR, ANALGESICS, ANTIDEPRESSANT, ANTIDIARRHEA, OR HYPOTENSIVE AGENT | ROQUES BERNARD (FR) | 1986-10-21 | — | — | US | disclosed |