Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870707 | 0.85 | KDM4E (0.41) | PDE2AKDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL9404035 | 0.76 | ALDH1A1 (0.48) | PDE2AKDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL31256398 | 0.76 | ALDH1A1 (0.48) | PDE2AKDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL10525468 | 0.75 | PDE2A (0.46) | PDE2AKDM4EALDH1A1TDP1 | |
| SCHEMBL900648 | 0.72 | PDE2A (0.44) | PDE2AKDM4EALDH1A1TDP1HTR2A | |
| SCHEMBL18247943 | 0.72 | PDE2A (0.44) | PDE2AKDM4EALDH1A1TDP1HTR2A | |
| SCHEMBL900649 | 0.72 | PDE2A (0.47) | PDE2AHTR2AHTR2CHTR2BLMNA | |
| SCHEMBL18247898 | 0.69 | ALDH1A1 (0.49) | PDE2AALDH1A1TDP1LMNAMAPT | |
| SCHEMBL3627129 | 0.68 | ALDH1A1 (0.54) | PDE2AKDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL900701 | 0.68 | PDE2A (0.41) | PDE2APTPRZ1PTPN1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315862-B1 | Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation | BAYER AG (DE) | 1994-04-13 | — | — | EP | claimed |